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Chronic renal disease is a condition that can cause the progressive deterioration of kidney function. If left untreated, the condition gradually gets worse with time, eventually leading to end-stage renal disease and organ failure. 

Chronic venous insufficiency occurs when malfunctioning valves in the leg veins prevent blood from flowing back to the heart. 

Cancerous cells in the large intestine/colon, usually beginning with polyps

Lumps of cells located on the colon, rectum, or both, which could develop into colorectal cancer