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Blood Clotting Disorders (Thrombophilia) Overview

Thrombophilia, also known as hypercoagulation, is a condition that increases the tendency of a patient’s blood to form clots. It is not a singular condition, but rather refers to a group of excessive blood clotting disorders, which may result in serious medical problems. Hypercoagulation can be broken into two broad categories, inherited and acquired. In patients with inherited thrombophilia, there is a preexisting genetic factor (or factors) that causes an abnormal tendency toward clotting. In cases where the condition is acquired, the increased tendency toward clotting may be caused by behavioral factors, such as smoking, or the development of certain diseases.

To schedule an appointment with the Heart and Vascular Institute, call 813-844-3900 or email

In many cases, thrombophilia is mild and unlikely to cause any serious medical complications. However, in some patients, this condition may result in the formation of blood clots than can cause serious and potentially life-threatening conditions, including but not limited to:

Tampa General Hospital has a team of vascular physicians, surgeons, interventionists and other specialists that are experienced in treating thrombophilia and other conditions of the blood and vascular system. If patients develop more serious problems, such as a pulmonary embolism, we can provide life-saving medical and surgical interventions in our state-of-the-art facility.