Pancreas Transplant Selection Criteria
Any adult with the diagnosis of Type I diabetes with Chronic Kidney Disease (CKD), Stage V or End Stage Renal Disease (ESRD), Stage VI, may be considered a candidate for transplantation evaluation. Some CKD, Stage IV patients may also be considered.
Absolute Contraindications to being considered for transplant:
- Active malignancy (cancer)
- Positive HIV status
- Severe cardiac and/or peripheral vascular disease that cannot be corrected. Severe cardiomyopathy with an Ejection Fraction < 25%.
- No insurance coverage or ability to handle expenses involved with transplant
- Inadequate support system (family, friends, etc. to help care for the patient)
- Documented history of non-compliance with medical regimen and/or medications without reasonable justification
- Severe pulmonary hypertension that cannot be controlled or treated
- Patients > 80 years.
- BMI > 40
- Uncontrolled or active psychiatric disorders
- Active substance abuse (drugs, alcohol, etc.)
Relative Contraindications (depends upon particular patient and degree of illness):
- Active or chronic untreated infections
- History of malignancy within past 2-5 years
- Active immunologic disorders potentially impacting the transplanted graft
- History of significant cardiac and/or peripheral vascular disease with active tobacco use
- Non-intact urinary tract or no viable diversion
- BMI between 35 and 40
- Active Hepatitis B or C
- Highly sensitized (high antibody level) patients and those patients nonresponsive to treatment